Felix, 26, is the overwhelming favorite to do just that. In fact, according to Olympics.betting-directory.com, she is a bigger favorite to win this race than Jamaica's Usain Bolt is to win the men's 200.
This is easily Felix's best event, and she appears to be running it better than ever. She won the U.S. Trials with a time of 21.69 seconds, and that was comfortably better than anything anyone else qualified with.
Still, when it comes down to one race—and just over 20 seconds of action—anything can happen, and if Felix has a slight misstep, in the 200-meter final will on Wednesday, Aug. 8, at 4 p.m. ET, here are three women who will be ready to pass her.
Shelly-Ann Fraser-Pryce, Jamaica
Who will win this race?
Fraser-Pryce has the speed to win. Her gold in the recent 100 proves that much. She is still coming into her own in the 200, and it was a slight surprise when she won the 200 at the 2012 Jamaican Olympic Trials with a time of 22.10.
Fraser-Pryce is looking great at these Olympics, and while she has never posted a time in the 200 that would suggest she is ready to take down Felix here, there is a chance that she is just hitting her stride in this event and will pull out a personal best in the final.
Carmelita Jeter, USA
Carmelita Jeter is another sprinter who is better in the 100, but she has put up some great results in the 200. She narrowly beat Felix at the 2011 World Championships to take silver. However, Felix has been getting the better of her most recently.
Jeter, 32, is still at the top of her game, and she is coming off of a silver in the 100 where she ran the fastest time in history to not win a gold.
Veronica Campbell-Brown and defending 100-meter champion
The reason Felix has two silvers instead of two golds in this event is this lady. Veronica Campbell-Brown is the two-time defending Olympics gold medalist.
She has not looked as strong this year in this race, but this decorated champ may have just been saving everything for London.