Reggie Wayne, Indianapolis Colts
Sure, he's aging and he may not be quite as fast as he once was. Oh yeah, and he's playing with a rookie quarterback.
Not to worry. Wayne isn't playing with any typical rookie QB in Andrew Luck, the No. 1 overall pick. Luck also has his college roommate, Coby Fleener, as a big tight end target to throw to.
Since tight ends are becoming more and more prominent in the NFL, the built-in chemistry between the Stanford teammates will make them dangerous.
That's where things will open up for Wayne. Three of the previous four seasons before 2011, Wayne had at least 100 receptions.
Even though last year was his first since 2003 without reaching 1,000 yards, he still got close with a slew of horrific quarterbacks throwing him the ball.
Imagine what he can do with Luck at the helm.
Pierre Garcon, Washington Redskins
It's worth mentioning Garcon next, since he was Wayne's teammate last year during the Colts' abysmal season. He, too, nearly reached the 1,000-yard mark in what was a career year.
Now, as the No. 1 target in Washington, he will also be catching passes from a rookie in Robert Griffin III.
Griffin has an unprecedented set of skills: a combination of blinding speed and polished passing ability.
ESPN NFC East blogger Dan Graziano discussed how good Griffin looks throwing the ball in training camp, but expressed concern over a suspect offensive line.
Translation: Griffin is a wonderful deep passer from the pocket, but he will likely be his most dangerous as a rookie on the outside.
Garcon is a deep threat, but his speed will also allow him to get open on broken plays, which could translate to huge gains for the Redskins offense.
On top of that, the Redskins' division is loaded with suspect secondaries. The atmosphere is prime for Garcon to post his first 1,000-yard year and have a huge yards-per-catch average with Griffin at the helm.
Denarius Moore, Oakland Raiders
Going back to Carson Palmer's potential for a breakout year, Moore is a younger player who had his coming out party late last year.
The rookie fifth-round pick wound up fourth in the NFL with an 18.7 yards per catch average, and managed to score five TDs on just 33 catches.
Moving forward, Moore should be the No. 1 option for Palmer. They have had a full offseason together, and developed a surprising amount of rapport even though Moore was so raw.
If you can get a top QB on a fantasy team with his top receiver, the results could be phenomenal. This would be a potentially cost-effective way of doing just that.