There are very few meaningless games in the NFL. With only 16 games in the regular season, one less win could mean the difference between 9-7 and 10-6, or a high seed versus a low seed. Unlike a sport such as baseball, where there seems to be an infinite number of games per season, every game in the NFL is a must-win game.
It is also true, however, that some games simply carry more weight. Whether that is because of the divisional rivalry, tiebreakers, or a gradient of the strength of one's team, consistent playoff teams are well-respected because they win the games that they should.
Last season, the Philadelphia Eagles lost many games that they shouldn't have. As a result, despite their late-season run, they missed the postseason. This season, they must find a way to win these must-win games or they will fall short of their playoff goals once again.