The Dutch club is revered worldwide for the undoubted quality that has come through what seems like the revolving door of its academy.
Marco Van Basten, Patrick Kluivert, Frank Rijkaard and the mercurial Johan Cryuff are just some of the household names that we can thank the Dutch club for introducing to the world.
Now it seems two of the new breed could be set for moves away, but could their destination be England and the Premier League?
One of those is reportedly Russian outfit Zenit St Petersburg, but the 20-year-old has previously spoken of his desire to join either Barcelona or Sir Alex Ferguson's side.
Speculation of his exit was raised after his club signed Adam Maher for AZ Alkmaar, who could act as a replacement.
Possessing a speed in spotting openings and quick decision making it is no doubt this creativity that stands out as a primary attribute, but could this ensure he is a success in England should he arrive?
This has led Vernon Anita to continue to be linked away from the reigning Eredivisie champions.
Speaking to the Sunday Mirror, Anita's agent Harry Lulofs said: “There is serious interest from Newcastle. A move to the Premier League is so tempting for him. We have to resolve the situation quickly.”
The player himself added: "I’ve two years left on my contract. But I want some clarity from Ajax about my future. We are having a meeting with Marc Overmars, the club’s new sporting director, to get a clear view of what the club wants.”
Would the man who is equally adept at left-back and defensive midfield be a good addition at the Sports Direct Arena?