Cain benefited from a full-extension diving grab by right fielder Gregor Blanco in the seventh inning. Blanco bee-lined to triple's alley and made a sensational grab on the warning track.
Cain is just the 22nd pitcher in Major League Baseball history to record a perfect game, the first by a member of the San Francisco Giants (only took 130 years).
The Twitterverse went ballistic as Cain recorded his final out:
Cain did it in style, striking out 14, tied for the most in perfect game history. What a moment for the @Giants franchise.— Sports Illustrated (@SInow) June 14, 2012
Ted Barrett was also the home plate umpire for David Cone's perfecto on July 18, 1999.— ESPN Stats & Info (@ESPNStatsInfo) June 14, 2012
Matt Cain hugs Buster Posey after throwing the first perfect game in Giants history. A very special moment twitpic.com/9w7phn— Bleacher Report (@BleacherReport) June 14, 2012
Congratulations to Matt Cain on his majestic night on the mound!