The waiver wire is a very interesting beast. One day you could scour the wire and find nothing but trash, and the next day a beacon of light could be found.
In order to truly dominate the waiver wire and stay ahead of your fellow GMs, you need to act quickly, have a method to your madness and be willing to pick someone up earlier than you would want.
The perfect example for me is Allen Craig. I had him tabbed as my 2B all season and drafted him even though he was out for a month.
I then had Kelly Johnson man 2B in the interim, and when Craig came back he reaffirmed my foresight (although he just hit the DL again).
This piece will discuss six hitters that you should target ASAP.
Note: As previously mentioned, the waiver wire is weak, and these suggestions are for deep leagues (12 teams or more).