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Number of times done: 21
Sure, more guys captured this achievement than others on the list, but there's no denying the validity of a perfect game.
Twenty-seven batters faced. Twenty-seven batters down.
Pitchers have to rely somewhat on their team for this.
They have to hope first and foremost their team scores enough runs. If an offense can't score a run, the less likely it becomes the starting pitcher can maintain a suitable pitch count.
Pitchers have to pray for no errors as well.
But mostly, the perfect game remains in the pitcher's hands (or just one hand).
Not one batter can make it to base.
Pitchers have to face opposing hitters, the crowd, their own mindset and fatigue for all nine innings.
The last to do it was Philip Humber of the Chicago White Sox on April 21, 2012.