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GK: David De Gea
An obvious pick.
LB: Patrice Evra
Patrice Evra is Manchester United's captain in the absence of Nemanja Vidic, so only injury will keep him out of the side.
By far United's best player at right-back, the Brazilian's defensive performances have improved as the season has wore on. In addition, his fluid partnership with Antonio Valencia guarantees his place in the team.
CB: Rio Ferdinand
This season, Rio Ferdinand has managed to keep the back issues, which have often caused him problems in the past, at bay. As such, he has been able to get regular play under his belt, which has helped his form and benefited the team.
CB: Jonny Evans
Recently referred to as "arguably the best defender in the country" by Sir Alex Ferguson, Jonny Evans has been one of United's best performers in this league campaign, and is sure to start against Everton.