Le: After suffering a brutal defeat at the hands of Wanderlei Silva, it will be interesting to see how Le bounces back from the loss. Franklin is a more technical fighter than Silva and should make for a better match-up in the stand-up department.
The key for Le is to keep the fight standing, using his unorthodox strikes to baffle Franklin while avoiding the ground. While Le's wrestling may be better than Franklin's, I doubt that the former Strikeforce champ would want to get into a grappling war with "Ace," who has a solid BJJ background.
Also, Le needs to avoid the clinch and use his distance as a clinch battle, or war against the cage will be an advantage for Franklin.
Franklin: In the past, Franklin has had trouble against top tier strikers, having lost to Lyoto Machida, Anderson Silva and Vitor Belfort. Le may not have the same skill sets as these formerly mentioned fighters, but his Sanshou style will pose a serious problem for Franklin.
If he chooses to keep the fight standing, Franklin needs to make it a dog fight and really test Le's chin, which has come into question after his losses to Wanderlei Silva and Scott Smith. If he can't keep it close and work off the cage or in the clinch, Franklin needs to take the fight to the ground, where he will have a shot at a submission.