NCAA Tournament 2012: Sweet 16 Picks Against the Spread

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NCAA Tournament 2012: Sweet 16 Picks Against the Spread
Andy Lyons/Getty Images

The Sweet 16 is just about 24 hours from tipping off, which means that it's about that time to check out the odds and make those picks. But with the matchups so close and the stats just about even, making picks in these rounds can become a little exhausting.

That's why I'm here to try and help you feel a little more comfortable about your picks.

How many double-digit seeds will advance to the Elite Eight? Who will get upset and sent home a bit earlier than they would like? Which teams have the advantage in the one-versus-four matchups? All of those questions and more are answered, as we dive into the Sweet 16 matchups.

Picking mascots and team colors is over with; this is the time where doing a bit of research pays off and will help you earn the big bucks. Here are predictions against the spread for the Sweet 16 matchups. 

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