The Bills missed out on Robert Meachem when he landed in San Diego, but they did get Stevie Johnson re-signed before free agency started and now would like to add another receiver. The San Francisco 49ers and Miami Dolphins are also involved with Manningham, so Buffalo may have to shell out some cash to get him in the fold.
Manningham is visiting the 49ers on Thursday, and with only Randy Moss (who is a big question mark) and Michael Crabtree at receiver, San Francisco can probably promise the 25-year-old Michigan product a significant role in the team's offense.
After packing up problem child Brandon Marshall and shipping him to the Chicago Bears, the Dolphins are also desperately in need of receiver help. They could probably pitch Manningham on a role as the team's top wideout.
But the Bills will be riding the momentum of snagging one of the biggest prizes in free agency and may be able to use the enthusiasm surrounding the Williams deal to help reel in Manningham. If he gets out of the Bay Area without a contract, I get the feeling the Bills have a legitimate shot at landing him.
They could certainly promise him a big role on the team and possibly a position as a leader considering he'll be bringing a Super Bowl ring to town.
If Buffalo plays this right, they could come out of the first week of free agency with the top defensive player available and a solid No. 2 receiver.