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What? No Eli Manning on the list?? It's an outrage! Calm down Giants fans. If you are thinking technically, Eli was not really drafted by the Giants. He was acquired via trade with the San Diego Chargers. The 2004 first round pick credited to the New York Giants is Phillip Rivers.
It may be considered the best trade in Giants history, but he was not a draft pick. The trade was constructed after each team had made their selections, not beforehand (like with the Redskins and Rams this year).
There is something poetic about Chris Snee being the best pick of the Tom Coughlin era, considering he's married to Coughlin's daughter.
When I was coming up with this list, and I omitted Eli due to the technicality, my thoughts went straight to Snee.
He has anchored the offensive line pretty much from day one, when the Giants made him the second best acquisition on draft day 2004.
He started 11 games as a rookie, then from 2005 to 2010 he became one of the best right guards in the business and did not miss a single start.
He ended his consecutive starts streak in 2011 and had a down year (as down a year as a Super Bowl champ can have), but he is still the best offensive lineman on the team and the best player drafted by the Giants since 2004.