GK: David de Gea
David de Gea has been one of United's best players in the last few weeks and it's unlikely Ben Amos will be selected ahead of him.
LB: Patrice Evra
Patrice Evra's performances have improved of late, but he is still prone to an error or two. Nevertheless, I expect him to again deputize as captain in Nemanja Vidic's absence.
RB: Rafael da Silva
It's astonishing that Sir Alex Ferguson chooses to forego playing his natural right-back in place of center-backs like Phil Jones and Chris Smalling. That being said, I expect Rafael to make a return to first-team affairs.
CB: Rio Ferdinand
Rio Ferdinand had a great shout for the Man of the Match award against Tottenham Hotspur and has been in form of late. If Sir Alex thinks to rest him, Chris Smalling may be the one to take his place.
CB: Jonny Evans
Assuming Sir Alex chooses to not stick with his first choice center-back partnership of Jonny Evans and Rio Ferdinand, I'd pick Evans to make the cut.