Juan Mata got the scoring underway with a calm finish from six yards out. Drogba played the ball over to Sturridge on the right of the box. His low cross was dealt with poorly by Napoli centre-back Paolo Cannavaro, who did nothing but deflect it behind him and into Mata’s path.
Napoli would equalize within 10 minutes. Ezequlel Lavezzi found a pocket of space just outside of the Chelsea box, and his curling shot did just enough to beat Cech to his left-hand side.
Edinson Cavani gave the home side the lead just before half. A ball crossed from the right of the box had the Chelsea defenders mesmerized as Cavani sneaked behind to put it away.
Chelsea picked it up in the second half, but was undone by a clear moment of David Luiz stupidity. The Chelsea defender decided it better to play the ball than clear it with Cavani breathing down his neck. Cavani made him pay by stealing the ball and feeding it to Lavezzi for his second goal of the match.
Chelsea now heads back to Stamford Bridge, where they will have to make up the deficit if they want to continue in Champions League and almost surely if Villas-Boas wants to keep his job.