The Orioles have made some significant changes this offseason and the lineup on Opening Day 2012 will only slightly resemble that of 2011.
In early 2011, Brian Roberts was ready to put his injuries in the past and get a full season under his belt. Vladimir Guerrero started at DH and Derrek Lee was the first baseman. 2010 Most Valuable Oriole, Luke Scott, was patrolling left field.
Now, Roberts is trying again to stay healthy and is not guaranteed to be ready by April 6. Vlad and Derrek Lee are both looking for jobs and Luke Scott was non-tendered, only to take a job in the division as the new DH in Tampa.
Like the Orioles, the Twins don't have a true ace, so I'm going to go with history and say that Carl Pavano will start his second straight Opening Day for the Twins.
Here is a look at what Buck Showalter may write on the lineup card for April 6.