Carmelo Anthony and Amar'e Stoudemire will try to find an answer to their recent struggles, while Deron Williams and the New Jersey Nets are hoping to pull of an upset.
The showdown in the Big Apple features a plethora of All-Star talent, yet both teams have found their fair share of struggles this season.
The Knicks come into this contest playing as poorly as any team in the NBA. Anthony and company have lost 11 of their last 13 games, as the downward spiral only seems to be getting worse for this team.
An inability to defend and a lack of movement on the offensive end has put the Knicks' playoff hopes in serious jeopardy. The team ranks No. 24 in assists per game and No. 20 in rebounds per game.
The Nets are looking for the team's second win in three games. New Jersey will have a chance to prove their worth in what will be a telling game in determining rest of the team's season.
Here is everything NBA fans need to know about this marquee matchup.
Where: New York, New York @ Madison Square Garden
When: Saturday, Feb. 4, 2012 @ 7:30 PM EST
Watch: MSG, YES
Listen: WFAN 660, ESPN 1050 (New York)
Betting Line: According to Predictem.com, the New York Knicks are three-point favorites heading into the matchup.
Key Injuries: The Knicks are still without their PG Baron Davis, while Stoudemire continues to play while still dealing with an ankle injury.
The Nets have SG Anthony Morrow listed on the injury report, as he is also tending to an ankle injury. In his last outing, Morrow scored a whopping 42 points.
What They're Saying: Amare Stoudemire is already talking about the game on Twitter, making clear that this is going to be a big win for the team.
"Let's win tonight Knicks, we have to play with heart, smarts an together. We are only as strong as our weakest link. Lets go!!"
Most Important Player to Watch: Anthony Morrow.
In his last outing, Morrow went off for 42 points and made Deron Williams and himself look like the most dynamic back court in basketball. The two combined for 54 points, 16 assists (14 by Williams) and nine rebounds.
Expect big things from Morrow if the Nets decide to pull off the upset in this one.
Prediction: Despite the Knicks' major struggles as of late, it will be all the more reason to beat a team that they are clearly more talented than. The Knicks and Nets don't differ much in record, but talent-wise, the Knicks undoubtedly have them beat.
After taking the Celtics down to the final seconds, expect the Knicks to take care of business and beat a team they should and will beat.