With the long and successful history both clubs boast, there is no shortage of hatred and every time these two meet there are usually a lot of implications at stake.
Fans of both clubs will remember the first meeting this season between the two pretty clearly, even if it is met with different feelings.
Manchester United downright thrashed the Gunners at Old Trafford back in August, punishing Arsene Wenger’s side en route to the most embarrassing defeat in the Frenchman’s spectacular Arsenal career. Every facet of the game was dominated by the Red Devils and this extraordinary match will weigh heavy on the minds of Wenger’s men.
But both have experienced a bit of a tumble as of late, failing to string together some consistency. And for the Gunners, this could be exactly the situation needed to exact some revenge.
Here are five things the Gunners must keep in mind if they are to get even this time around.