It is highly unlikely that Mourinho will use this starting XI on Wednesday. The Portuguese tactician may opt for the 4-3-3 formation, but the inclusion of midfielder Esteban Granero is doubtful.
This lineup could provide the perfect balance of defensive fortitude and attacking creativity that can defeat Barcelona. The 4-3-3 system should have more success against Barcelona than the standard 4-2-3-1 formation because the likes of Xavi and Iniesta cannot dominate the midfield.
With Coentrão, Alonso and Granero in midfield, Madrid will not get overrun in midfield by Barcelona's little maestros. When Madrid play with the 4-2-3-1 system, Barcelona's playmakers receive too much time and space on the ball.
Although Granero is not a natural defensive midfielder, he can close down opponents and track back defensively. The Spaniard may not be a world-class player, but he can be effective against Barcelona.
Granero has good touch, creativity and vision. The former Getafe player is a more accomplished passer than Khedira or Lass. Therefore, when Barcelona press high on Alonso, Granero can distribute from midfield and drive the team forward.
Granero's range of passing and skill could provide great balance for this three-man midfield. In addition to the balanced midfield, Madrid would be able to keep the world-class partnership of Pepe and Sergio Ramos at the back.
Although Mourinho will choose a different group of players this Wednesday, he should highly consider this starting XI against Barcelona.